Membranous Trial supports chlorambucil/prednisolone
Peter Mathieson presented preliminary results from the epic UK Membranous Trial at the recent RA/BRS meeting in Birmingham. These showed a highly significant benefit of 6 months treatment wtih prednisolone/chlorambucil (modified Ponticelli regimen) compared to cyclosporin or supportive therapy alone. The full results will be published soon.
The Trial was mainly funded by the MRC, with contributions also from Kidney Research UK, the Renal Association, and Novartis.