02/11/17

Update: Research at The UK Renal Registry (UKRR)

Access to UKRR data – In early 2017 we had a call for applications for UKRR data – the first call to follow the new process required by the Health Research Authority in 2016/2017. There was a good response, with 6 applications, 4 of which have proceeded to peer-review. These will be considered at the October UKRR Research Methods Study Group and a recommendation for data release made. If anyone is interested in applying for access to UKRR data for research or non-research purposes, please see: www.renalreg.org/about-us/working-with-us/

Registry trials – We also continue to make progress with registry trials. Analysis of the Health Foundation-funded Tackling AKI trial, led by Dr Nick Selby in Derby, is almost complete, with results accepted for presentation at a late breaking clinical trial session at the American Society of nephrology.  Please watch out for these results!

The first two UKRR-led randomised controlled trials are also now well into set up

  • The Prepare for Kidney Care study – a randomised controlled trial of preparing for renal dialysis vs preparing for responsive management (with parallel registry follow up studies to address generalisability)

Protocol: www.journalslibrary.nihr.ac.uk/programmes/hta/155739/#/

Trial manager email: sscm-prepareme-trial@bristol.ac.uk

  • The High-volume Haemodiafiltration vs High-flux Haemodialysis Registry Trial (H4RT) – a randomised controlled trial of high-volume HDF vs high-flux HD (with all follow-up being done by linkage to UKRR and hospital episode statistics/ office for national statistics).

Protocol: www.journalslibrary.nihr.ac.uk/programmes/hta/158052/#/

Trial manager: h4rt-study@bristol.ac.uk

These have been funded by the National Institute for Health Research, the NHS’s research funding body. We are still looking for sites for both trials, so please contact the trial managers above if you are interested.