Mitochondrial Disease affecting the kidney

Patient Information

In nearly every cell in the body, mitochondria are responsible for producing energy (called ATP). They are like power stations, supplying the energy our cells need to function.
Cells make up tissues and organs in our bodies, for example the heart and liver. If our cells do not have enough energy, the tissues or organs do not work properly. In much the same way, if power stations do not produce enough energy there will be areas of blackout, where parts of the country cannot function.

In nearly every cell in the body, mitochondria are responsible for producing energy (called ATP). They are like power stations, supplying the energy our cells need to function.
Cells make up tissues and organs in our bodies, for example the heart and liver. If our cells do not have enough energy, the tissues or organs do not work properly. In much the same way, if power stations do not produce enough energy there will be areas of blackout, where parts of the country cannot function.

Treatment is usually supportive, relieving the symptoms that can develop, for example, treating seizures with medication.
Doctors can also try to make energy production more efficient, using co-factors and vitamins. Examples of these are Ubiquinone (Coenzyme Q10), Thiamine and Riboflavin.
Some people find that using a special diet can help and this varies depending on which part of the energy production process is affected. However, this should only be tried with guidance from your metabolic team.
Any metabolic stress on the body, for example an illness, has the potential to cause a worsening or progression of Mitochondrial Disease. This maybe due to the cells not being able to cope with the extra demand put upon them.
It is difficult to live in a world where all potential metabolic stresses are removed. Therefore, it is important to be aware of these risks so that early medical advice and treatment of any illness can be started.
If you would like further information please visit our Questions and Answers page.

The Lily Foundation is the UK’s leading mitochondrial disease charity. Our mission is to improve the lives of people affected by mitochondrial diseases. We are working towards a future where mitochondrial diseases can be effectively treated or cured. 

https://www.thelilyfoundation.org.uk/

Guidelines

NICE accredited clinical practice guidelines 

Available here

22nd Annual Report

Analyses about care provided to patients at UK renal centres.

Read the report

UKRR AKI Report

A report on the nationwide collection of AKI warning test scores. 

Read the report